Barely Significant
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A Randomized, Double-Blind, Placebo-Controlled Pilot Trial With Open-Label Extension of Sirona, a Hydrogel for Weight Loss.

Obesity (Silver Spring) · 2026 · PMC12724022 · PMID 41090617

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a favorable trendno p-value reported
This suggests a favorable trend of an improvement in glycemia. 4 Discussion The primary objectives of this trial, to confirm tolerability, safety, and feasibility, have been met.

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