Efficacy and Safety of Oral Valiltramiprosate in APOE4/4 Homozygotes with Early AD: Topline Results from the APOLLOE4 Phase 3 Trial

Alzheimers Dement · 2025 · PMC12726020

Europe PMC

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did not achieve significanceno p-value reported

Conclusion In the overall population, ADAS‐Cog13 did not achieve significance, but the hippocampus showed significant 18% slowing of atrophy.

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