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Fibroblast-like synoviocytes mediate the generation of soluble PD-1 in an MMP-9-dependent manner: a novel target therapy for rheumatoid arthritis.

Front Immunol · 2025 · PMC12727936 · PMID 41451230

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a notable trendno p-value reported
Although no direct correlation with disease activity markers was found, there was a notable trend linking the proportion of PD-1 + T cells to disease activity indicators.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.