Western Diet Induces Changes in Gene Expression in Multiple Tissues During Early Insulin Resistance and Glucose Intolerance in Male C57BL/6 Mice.

Finally, our results suggest that beta cell dedifferentiation and neogenesis of pancreatic cell lineages occur simultaneously, most likely directed toward non-beta cell types, which may be significant for the development of therapies or dietary interventions aimed at prevention or targeted differentiation toward the desired pancreatic cell lineage.

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