highly significantp = 0.00072
Subsequently, CYPRI_cor was applied to the same patient cohort and yielded markedly stronger results, showing a highly significant association with the outcome measure IMPACT_orig (SE = 0.22; p = 0.00072), suggesting that the revised score maintains and potentially strengthens the relationship between CYPRI and clinical impact ( Figure 4 ) compared to the original model ( p = 0.0267).