highly significantp < 0.001
The statistical significance was defined as follows: * p < 0.05 (statistically significant), ** p < 0.01 (highly significant), *** p < 0.001 (very highly significant), and **** p < 0.0001 (extremely significant).
The statistical significance was defined as follows: * p < 0.05 (statistically significant), ** p < 0.01 (highly significant), *** p < 0.001 (very highly significant), and **** p < 0.0001 (extremely significant).