Computational characterization of peptide binding stability to HLA-C allotypes and its association with HIV-1 infection progression and HIV-1 related neurocognitive impairment.

Front Immunol · 2025 · PMC12738900 · PMID 41459481

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highly significantno p-value reported

This enhanced approach confirmed and strengthened our earlier findings, showing a robust and highly significant correlation between accelerated disease progression and a higher burden of unstable HLA-C allotypes.

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