Time in LDL cholesterol target range and major adverse cardiovascular events risk: A pooled analysis of two cohorts.

Am J Prev Cardiol · 2025 · PMC12746287 · PMID 41473015

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The highest LDL-C TTR quartile was associated with a 25 % reduction in MACE (HR: 0.75, 95 % CI: 0.68 to 0.83), 42 % reduction in myocardial infarction (HR: 0.58, 95 % CI: 0.49 to 0.68), 24 % reduction in stroke (HR: 0.76, 95 % CI: 0.64 to 0.91), and 13 % reduction in CVD death (HR: 0.87, 95 % CI: 0.76 to 1.00; borderline significance).

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