highly significantP < 0.0001
Box-Behnken design analysis yielded a highly significant quadratic model ( P < 0.0001) with a non-significant lack of fit ( P = 0.5929), indicating excellent model adequacy and reliability (R 2 = 0.9962).
Box-Behnken design analysis yielded a highly significant quadratic model ( P < 0.0001) with a non-significant lack of fit ( P = 0.5929), indicating excellent model adequacy and reliability (R 2 = 0.9962).