A Grading System of Intratumoral Tertiary Lymphoid Structure for Combined Hepatocellular-Cholangiocarcinoma: A Multicenter Pathological Study.

J Hepatocell Carcinoma · 2025 · PMC12747833 · PMID 41477585

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marginally significantno p-value reported

Specifically, compared to TLS-negative patients, iTLS (TLS 1 group) demonstrated marginally significant improvement in RFS and OS, while mature TLS (TLS 2 group) showed statistically superior RFS and OS.

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