Studying rare variant polygenic risk scores using whole exome sequencing and imputed genotype data.

Commun Biol · 2025 · PMC12749733 · PMID 41286096

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP = 1.21E-149actually significant

For five quantitative traits (BMI, DBP, FEV, RHR, and SBP), per-standard deviation (perSD) Beta values for rvPRS showed highly significant associations (max P = 1.21E-149; significance threshold P < 1.26E-04 = 0.05/18/22).

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