Association Between Circulating Cytokines and Psychosomatic Syndromes in Patients with Mood Disorders.

Clin Neuropsychiatry · 2025 · PMC12752928 · PMID 41477541

Europe PMC DOI

hedged sentence

0.0490

closest p · 1.0× alpha

0.0490

boldest claim

The sentences

marginally significantp = 0.049actually significant

The total effect of TNF-alpha on depressive symptoms was significant (c = 6.32, SE = 1.84, t = 3.44, p = 0.001), when controlling for PHQ-15, the direct effect remained marginally significant (c' = 2.99, SE = 1.50, t = 1.99, p = 0.049), suggesting a partial mediation of PHQ-15 ( figure 2 ).

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