Decoding the germline genetic architecture of prostate cancer at a single cell resolution.

PLoS Genet · 2025 · PMC12753072 · PMID 41468516

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highly significantno p-value reported

Our primary interest focused on the upper-right corner in Fig 5B , where variants not only exert strong regulatory effects in LE-2 (high absolute DEEP+ scores) but also display the highly significant prostate cancer GWAS risk (large |Z|-scores).

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