A homology-based 3D model and structure-function studies reveal key elements for divalent metal ion transporter ZIP8 (SLC39A8) function.

J Biol Chem · 2025 · PMC12753238 · PMID 41232668

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highly significantno p-value reported

The cells overexpressing ZIP8 showed a highly significant increase in intracellular pH upon perfusion with both Zn 2+ and HCO 3 - ( Fig. 7 B ), compared with those overexpressing the EV.

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