MicroRNA-26b-/- augments atherosclerosis, while mimic-loaded nanoparticles reduce atherogenesis.

Apoe −/− Mir26b −/− mice showed a highly significant 2.8-fold increase in plaque size in the aortic arch ( Figure 1 B and C ), whereas plaque size in the aortic root was not affected (see Supplementary material online , Figure S1 ).

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