rs9789446 genotype as susceptibility biomarkers for congenital hypothyroidism based on population and family validation.

Front Genet · 2025 · PMC12755854 · PMID 41480151

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highly significantno p-value reported

In the male subgroup, this association was highly significant, and the dominant model revealed the strongest effect, indicating that male carrying the G allele had a significantly lower risk of CH (OR = 0.566, 95% CI 0.371–0.862, p = 0.008, FDR q = 0.032).

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