a nonsignificant trendp = 0.139
The pooled analysis of four studies 42 45 49 51 found a nonsignificant trend for benefit for routine platelet transfusion when PLT falls below 50 × 10 9 cells/L, with an odds ratio of 0.84 (95% CI, 0.46–1.58, p = 0.139, I 2 = 45.5%).