Barely Significant
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The trend analysis of HIV and other sexually transmitted infections among women of childbearing aged 15 to 49 years from 1990 to 2021 and its forecasting from 2022 to 2030.

Front Public Health · 2025 · PMC12757296 · PMID 41487650

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an apparent trendno p-value reported
Analysis by SDI regions An apparent trend emerged across SDI regions ( Table 2 ), where higher SDI levels were generally associated with lower HIV incidence.

also in 709 other papers

an increasing trendno p-value reported
However, from 1990 to 2021, STI-related DALYs showed an increasing trend in Western Europe, Tropical Latin America, the Caribbean, and the High-income Asia-Pacific region, whereas all other GBD regions experienced a decline.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.