Integrative analysis of Helicobacter pylori-driven stomach adenocarcinoma reveals epigenetic deregulation, immune evasion, and therapeutic resistance.

Hereditas · 2025 · PMC12764169 · PMID 41291892

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0.0480

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an increasing trendP = 0.048actually significant

Evaluation of gene expression across pathological stages of STAD revealed an increasing trend of COL4A1 expression with disease progression, reaching statistical significance between stage I and stage IV ( P = 0.048), whereas THBS2, CTNNB1, and E2F3 showed no significant stage-dependent variation (Fig. 2 C).

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