highly significantP < .001
For the DAOM genotype, ANOVA tests revealed highly significant between-cluster differences across all node-level metrics (degree: F = 1107, P < .001; average path length: F = 6734, P < .0001; clustering coefficient: F = 482.4, P < .001; betweenness centrality: F = 8.2, P < .001.For the C2 genotype, cluster membership significantly affected degree ( F = 719.2, P < .001), average path length ( F = 1291, P < .001), and clustering coefficient ( F = 436.2, P < .001), but not betweenness centrality ( F = 2, P = .089).