Antibody responses to a highly conserved peptide in HCV E2 protein correlate with chronicity or spontaneous clearance of HCV infection.

Proc Natl Acad Sci U S A · 2026 · PMC12773747 · PMID 41481431

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantP < 0.0001actually significant

marginally significantP = 0.0468actually significant

Using α=0.05 as the significance threshold, our analysis revealed a highly significant difference at F442 ( P < 0.0001) and a marginally significant difference at F447 ( P = 0.0468).

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