A structure-guided approach to noncoding variant evaluation for transcription factor binding using AlphaFold 3.

Nucleic Acids Res · 2026 · PMC12774635 · PMID 41495882

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highly significantno p-value reported

1a demonstrates that all three metrics separated the SNP-SELEX preference groups, with highly significant differences between the ref., alt. , and non-pbSNP groups.

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