A novel two-sample Mendelian randomization framework integrating common and rare variants: application to assess the effect of HDL-C on preeclampsia risk.

Brief Bioinform · 2026 · PMC12777983 · PMID 41499219

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marginally significantno p-value reported

Statistically, the estimated effect was marginally significant but consistent with prior studies [ 19 , 34 , 35 ].

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