Circadian Clock Dysfunction Exacerbate Autistic-Like Behaviour and Wnt/β-Catenin Signalling Dysregulation in ASD Mice and Treatment of Melatonin.

J Cell Mol Med · 2026 · PMC12779517 · PMID 41501308

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a decreasing trendno p-value reported

In previous studies, researchers using proteomics have confirmed that the Wnt pathway is highly enriched and upregulated in ASD mice, while phosphorylated β‐catenin levels exhibit a decreasing trend [ 27 ].

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