Barely Significant
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The validated French CFAbd-Score reveals a lower burden of gastrointestinal symptoms in patients on Elexacaftor/Tezacaftor/Ivacaftor.

J Pediatr Gastroenterol Nutr · 2026 · PMC12780474 · PMID 41181888

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highly significantno p-value reported
Nevertheless, the present cohort of pwCF with heterogeneous ETI therapy status reveals highly significant and clinically meaningful differences in AS of pwCF with and without treatment with the highly effective CFTR modulator.

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