Total neoadjuvant therapy for locally advanced rectal cancer: barriers to implementation in real-world practice.

J Cancer Res Clin Oncol · 2026 · PMC12783395 · PMID 41504807

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a favorable trendno p-value reported

A reduced incidence of a severe LARS with rates of 9% in the TNT and 22% in the non-TNT-group ( p = 0.23) showed a favorable trend of functional outcome in the TNT group.

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