PUMA-p53 Dysregulation and Ki-67 Overexpression Define Unfavorable Prognostic Signatures in Colorectal Cancer.

Cancers (Basel) · 2025 · PMC12784786 · PMID 41514585

Europe PMC DOI

hedged sentence

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

marginally significantp = 0.068so close (0.05 < p ≤ 0.1)

Low Ki-67 expression was significantly associated with longer OS ( p = 0.03) Similarly, the combination of low expression of p53 and PUMA in TC of primary tumors showed a marginally significant association with OS ( p = 0.068).

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