a decreasing trendp = 0.0730
In AD, Opa-1 levels demonstrate a decreasing trend ( p = 0.0730) while Drp-1 shows an increasing tendency ( p = 0.3236), though without statistical significance, associated with markedly elevated Mfn-2 levels ( p ≤ 0.0001) compared to aging cases ( Figure 5 D–F). 2.5.