Genetic Link Across Species: SIX6, a Major Human Glaucoma Gene, Confers Susceptibility to Glaucoma in Shiba-Inu Dogs.

Invest Ophthalmol Vis Sci · 2026 · PMC12786397 · PMID 41533905

Europe PMC DOI

hedged sentence

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

borderline significanceP = 0.056so close (0.05 < p ≤ 0.1)

rs850948063, which is in moderate-to-strong LD with rs24543691 in both breeds, also showed a similar effect size (OR, 1.66) but only borderline significance ( P = 0.056).

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