Barely Significant
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Artificial Intelligence-Enhanced Molecular Profiling of JAK-STAT Pathway Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer.

Int J Mol Sci · 2026 · PMC12786996 · PMID 41516350

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highly significantno p-value reported
Despite the imbalanced sample sizes, the automated statistical testing, based on a 2 × 2 contingency framework, yielded a highly significant p -value (0.093 for the chi-square test) and an odds ratio of 0.0 (95% CI: 0.045–0.193), indicating a marked disparity in KRAS mutation representation at the exploratory stage.

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