Comparative Evaluation of Salivary and Serum Levels of Uric Acid (UA) and Lactate Dehydrogenase (LDH) among Patients with Periodontal Disease: A Biochemical Study.

demonstrated raised salivary LDH in periodontitis patients, advocating for its use as a noninvasive diagnostic marker.[ 8 ] A moderate positive correlation (r = 0.582, P < 0.001) was found between serum and salivary LDH levels, aligning with findings from Havle et al ., who reported a significant correlation between the two fluids.[ 9 ] However, some studies by Peña et al .[ 10 ] found inconsistent associations between serum and salivary LDH levels, likely due to variations in study designs or populations.[ 4 ] Uric acid levels in saliva showed a decreasing trend from Group 1 to Group 3, while serum UA levels were highest in Group 1.

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