Across life cycles, there was an increasing trend in ASPR of RA, where childhood remained low at 0.02, then increased to 172.84 in adolescence, after downward to 150.95 in the middle and young-aged cycle, the ASPR was increased to 209.35 in the middle and old-aged cycle (Table 1 ; Table S1, Supplemental Digital Content, https://links.lww.com/MD/R133 ; Fig. 1 G).
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Global landscape of autoimmune diseases across different lifespan: A three-decade perspective.
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Birth cohort effect findings indicated a decreasing trend in the relative risk of IBD among consecutive birth cohorts, individuals who were born between 1920 and 1929 have the highest IBD risk (Table S5, Supplemental Digital Content, https://links.lww.com/MD/R133 ).