Evaluating carboplatin and PARP inhibitor combination efficacy using high-grade serous carcinoma spheroids and organoids.

Cancer Biol Ther · 2026 · PMC12795296 · PMID 41520277

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an apparent trendno p-value reported

However, iOvCa195 organoids displayed increased efficacy with niraparib and carboplatin direct combination treatment; although not significantly different, there was an apparent trend for the same effect with olaparib and carboplatin in the iOvCa195 organoids ( Figure 4B ).

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