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Secondary Risk-Reducing Strategies for Contralateral Breast Cancer in BRCA1/2 Variant Carriers: A Systematic Review and Meta-analysis.

Adv Ther · 2025 · PMC12795943 · PMID 39609372

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an increasing trendno p-value reported
(2016), who suggested an increasing trend of tamoxifen efficacy in reducing CBC risk among the general patients with breast cancer.

also in 63,971 other papers

a decreasing trendno p-value reported
Our study indicates a decreasing trend of tamoxifen efficacy in reducing CBC risk among BRCA carriers who were ER-positive.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.