Animal product-free formation and cultivation of three-dimensional primary hepatocyte spheroids.

Drug Metab Dispos · 2025 · PMC12799525 · PMID 40945386

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an interesting trendno p-value reported

Besides the significant changes seen, an interesting trend was observed with many of the ADMET proteins showing decreasing expression levels over time in 3D PHH formed in FBS, whereas the corresponding proteins in SFM-formed 3D PHH did not show the same pattern but instead remained stable over time.

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