Barely Significant
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A humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the blood-brain barrier.

J Biol Chem · 2026 · PMC12799929 · PMID 41338456

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 0.001actually significant
More pronounced and highly significant reductions ( p < 0.001) were seen in all genotypes carrying either homozygous Tf h/h or Tfrc h/h alleles, consistent with a genotype-dependent shift in systemic iron distribution.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.