Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson's disease mouse model.

NPJ Parkinsons Dis · 2025 · PMC12800057 · PMID 41381624

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might be significantno p-value reported

Even though we did not measure this, which is a limitation in our study, our data do not suggest the presence of cytosolic DNA in amounts sufficient to lead to STING-mediated inflammation that might be significant for neuronal death.

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