ShRNA transfection of HSB-2 leukemic cell line for post transcriptional knockdown of CD46 and CD55 Flow cytometric analysis performed to measure the success of transfection showed a highly significant reduction in CD46 expression level following ShRNA - transfection by 91.42% compared to the mock transfected cells.
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The contribution of the membrane-bound complement regulatory proteins CD46 and CD55 in phases of acute lymphocytic leukemia and acute myelogenous leukemia.
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