Association of HLA class I allele and tuberculosis susceptibility: a systematic review and meta-analysis.

Sci Rep · 2025 · PMC12800256 · PMID 41361354

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borderline significanceno p-value reported

Subgroup analysis by sample size reported an association with TB when the sample size was less than 100, i.e ., (OR= 1.24, 95% CI= 0.30–5.22, p = 0.770) and more than 100 (OR = 2.04, 95% CI= 0.92–4.52, p = 0.080) with borderline significance.

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marginal significanceno p-value reported

Subgroup analysis done by sample size showed a protective trend when < 100 cases (OR = 0.82, 95%CI= 0.34–1.99, p = 0.659) and > 100 cases (OR = 0.74, 95% CI= 0.53–1.03, p = 0.071) with marginal significance.

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