Abnormal T-Cell activation and cytotoxic T-Cell frequency discriminate symptom severity in myalgic encephalomyelitis/chronic fatigue syndrome.

We found a moderate and highly significant ( p < 0.0001) correlation between the frequency of MAITs expressing CD69 and the frequency of NK cells, CD4 + T cells and CD8 + T cells expressing CD69 across all the samples (Spearman r = 0.697 for CD69 + NK cells, r = 0.508 for CD69 + CD4 + T cells, r = 0.649 for CD69 + CD8 + T cells, Fig. 5 a).

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