Barely Significant
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ctDNA Detected after Neoadjuvant Therapy for HER2-Positive Breast Cancer Is Associated with Inferior Outcomes and May Inform Adjuvant Therapy.

Cancer Res Commun · 2026 · PMC12802552 · PMID 41543393

Europe PMCDOI
1
hedged sentence
0.0510
closest p · 1.0× alpha
0.0510
boldest claim

The sentences

borderline significantP = 0.051so close (0.05 < p ≤ 0.1)
Patients with a non-pCR status had a borderline significant risk of recurrence (HR, 10.387; 95% CI, 0.992–108.801; P = 0.051).

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