Pharmacological intervention: Challenges and promising outcomes for fat loss and preservation of lean body mass in the treatment of overweight and type 2 diabetes.

Diabetes Obes Metab · 2026 · PMC12803604 · PMID 41178728

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a nonsignificant trendno p-value reported

In the full analysis set, a nonsignificant trend toward improvement was noted; however, in the per‐protocol population, a significant improvement of 0.09 m/s was observed in the 350 mg group, approaching the clinically relevant threshold of 0.1 m/s.

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