Transperineal Versus Transrectal Prostate Biopsy: A Systematic Review and Meta-analysis of Randomized Controlled Trials Across Settings With and Without Magnetic Resonance Imaging Targeting.

Subgroup analyses revealed a nonsignificant trend towards lower risk both in the subgroup of studies with MRI-targeted biopsy (OR 0.24, 95% CI 0.05–1.20) and the subgroup of studies without MRI-targeted biopsy (OR 0.43, 95% CI 0.13–1.35), both with no evidence of heterogeneity. 3.4 Acute urinary retention The overall risk of AUR did not differ significantly between the TP-Bx and TR-Bx approaches (OR 0.73, 95% CI 0.44–1.21; Table 3 and Supplementary Fig. 4 ).

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