Oncolytic adenoviruses encoding bispecific T cell engagers or a novel trispecific T cell engager for dual-targeting of c-MET and EGFR.

Mol Ther Oncol · 2026 · PMC12804148 · PMID 41552759

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highly significantno p-value reported

Therefore, we detected a highly significant increase in cytotoxicity for all TCE-encoding oAds already at titers far below the titers required to show oncolytic cytotoxicity.

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