Intestinal Epithelial Cell-derived Osteopontin Protects Against Metabolic Dysfunction-associated Steatohepatitis by Modulating Bile Acid Composition and the Gut Microbiome.

Cell Mol Gastroenterol Hepatol · 2026 · PMC12804385 · PMID 41241180

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a decreasing trendno p-value reported

Both IEC OPN loss and the MASH diet independently increased total BAs in portal serum and liver ( Figure 5 A ), whereas fecal BAs showed a decreasing trend.

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