Barely Significant
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Machine learning analysis of oral solid dosage formulation solubility variations by adjusting pressure and temperature.

Sci Rep · 2025 · PMC12808292 · PMID 41372385

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an increasing trendno p-value reported
The figure highlights the crossover pressure effect, where solubility behavior transitions from a decreasing to an increasing trend with temperature depending on whether the system is below or above the crossover point 25 .

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