Extracellular vesicles derived from adipose-derived mesenchymal stem/stromal cells prevent synovial inflammation and attenuate cartilage degeneration in rodent osteoarthritis.

Regen Ther · 2026 · PMC12809275 · PMID 41551961

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a decreasing trendno p-value reported

The mRNA expression levels of IL-1β and IL-6 showed a decreasing trend in the EVs-treated group, with the most notable differences observed between 4 and 6 h post-stimulation( Fig. 1 b).

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