Additionally, the Y maze test indicated no significant differences in working memory among Akap11-KO-Wt, Akap11-KO-Het, and Akap11-KO-Hom mice, despite observing a decreasing trend (alternation (%): Akap11-KO-Wt: 57.61 ± 3.438 s; Akap11-KO-Het: 49.83 ± 2.849 s, df Het = 40, t Het = 1.816, P Het = 0.0768; Akap11-KO-Hom: 52.26 ± 3.768 s, df Hom = 40, t Hom = 0.8654, P Hom = 0.3920) ( Supplementary Figure 6 and Supplementary Table1 ).
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Schizophrenia-Related Synaptic Dysfunction and Abnormal Sensorimotor Gating in Akap11-Deficient Mice.
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