This is likely to be significant given that the MDRD and CKD-EPI equations were derived and validated using US cohorts. 6 , 55 , 58 , 59 The more recent CKD-EPI-2021 (race-free) equation, which was developed to reduce the gap between Black and White ethnic groups in the USA had minimal South Asian representation and therefore was unlikely to address eGFR performance in South Asian cohorts.
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A Systematic Review Evaluating Estimated GFR Performance in South Asian Populations.
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