Network pharmacology of cellular targets in major depressive disorder and differential mechanisms of fluoxetine, ketamine and esketamine.

Comput Struct Biotechnol J · 2026 · PMC12810504 · PMID 41550142

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highly significantno p-value reported

With a highly significant p-value (5.74E-05), NFKB regulation of EGFR suggests its involvement in epidermal growth factor signaling, which is key to neuroplasticity and neuronal regeneration.

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